Projects of Area 2 - Biosynthesis, post-translational modifications and trafficking of recombinant proteins List of ongoing PhD research projects: RESEARCH PROJECT SUPERVISOR PhD STUDENT List of completed PhD research projects: RESEARCH PROJECT SUPERVISOR PhD STUDENT O-glycan engineering of N. benthamiana for structure-function characterization of human IgA1 Richard Strasser Valentina Ruocco Enzymatic properties and evolutionary origin of the cancer-associated protease cathepsin O Lukas Mach Nikolaus Kienzl Methylated N-glycans in moss – annoying or useful for biotechnology? Friedrich Altmann David Stenitzer Structure and Function of Hexosaminidases Iain Wilson Zuzanna Dutkiewicz Nsun5 methylates rRNA: 'specialized' ribosomes in stress resistance and aging Johannes Grillari Anja Wagner Specialized ribosomes: implications for protein synthesis, cell behaviour and health Johannes Grillari Fabian Nagelreiter Extracellular vesicle trafficking in aging Johannes Grillari Vera Pils Identification of Lewis a containing glycoproteins from Arabidopsis thaliana and characterization of their involvement in pathogen defence Richard Strasser Gernot Beihammer Characterisation of unusual glycosyltransferases from lower eukaryotes Iain Wilson Barbara Eckmair Isolation and functional characterization of Nicotiana benthamiana serine proteinases involved in the degradation of recombinant proteins Lukas Mach Alejandro Puchol Tarazona Enzymatic isotope−labeling of O-glycans for improved tumor biomarker analysis Friedrich Altmann Johannes Fuehrer Extracellular vesicle trafficking in aging Johannes Grillari Madhusudan Bobbili Analysis of structure−function relationships of monomeric and dimeric human IgA1 and IgA2 with defined N− and O−glycosylation Richard Strasser Kathrin Göritzer Engineering the interface of Fab fragments for the generation of bispecific antibodies Johannes Grillari Maximilian Bönisch Receptor specificity of the H1 hemagglutinin of the H1N1 swine−origin influenza A virus (S-OIV) Friedrich Altmann Laura Neumann Isolation and functional characterization of Nicotiana benthamiana papain-like cysteine proteinases Lukas Mach Melanie Niemer MAPK and JAK/STAT Signaling in Immune Regulation by Dendritic Cells Lukas Mach Klara Soukup Expression cloning of immunomodulatory glycan−modifying enzymes in insect cells Iain Wilson Simone Kurz